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Firms are subject to corporate
2024-05-20
Firms are subject to corporate taxation, and face either an ACE or a CBIT tax scheme. The two tax regimes achieve financing neutrality by treating debt and equity equally, but differ according to whether deduction of capital costs from the corporate tax all trans retinal receptor is allowed or not.
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Although CP has been an important research subject in the
2024-05-20
Although CP has been an important research subject in the field of antigen processing and presentation, the mechanisms of presentation of intracellular DBU by MHC II received considerably less attention. Interestingly, pioneering work by the Münz laboratory has pointed to an involvement of autophagy
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To maintain ATP levels postmortem muscle
2024-05-20
To maintain ATP levels, postmortem muscle mobilizes its glycogen reserves to yield HET0016 6-phsphate that proceeds through glycolysis. Glycogen degradation was affected by the interaction between treatment and time (P greater in samples containing mitochondria regardless of Na-azide (Pinitiation of
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Our outcrossing data confirmed that
2024-05-20
Our outcrossing data confirmed that ACL1 and ACL2 have important temporal and spatial functions in ascospore delimitation in G. zeae. When each ACL deletion mutant was used as male for outcrossing, nuclear division and spore delimitation were not properly progressed in most asci. Ascospores that con
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With regard to the first question subcellular
2024-05-20
With regard to the first question, subcellular fractionation studies revealed that BDK and PPM1K are clearly detectable in both the mitochondrial and cytosolic subcellular fractions, thus making it possible for these enzymes to interact with both the BCKDH and ACL substrates. The preferential presen
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The canonical binding sites to which or contribute are
2024-05-20
The canonical bromodomain inhibitor to which α2, α3, or α5 contribute are highly similar. Therefore, differences in ligand affinity will not be large even if a ligand makes optimal use of the small differences in the pockets. As a possible alternative approach to achieve separation of compound effe
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Arginase deficiency is a rare urea cycle
2024-05-20
Arginase deficiency is a rare urea cycle disorder with hyperargininemia and profound neurological impairment as hallmark features. Arginase-1-deficient mouse models have been created, and they exhibit a profound lethal phenotype approximately 2 weeks after birth in the global knockout (KO) mice or a
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br Conflicts of interest br Introduction Photodynamic
2024-05-20
Conflicts of interest Introduction Photodynamic Therapy (PDT) is a technique used for the treatment of several malignant and non malignant diseases (Akimoto, 2016, Keyal, Bhatta, Wang, 2016, Morton, Szeimies, Sidoroff, Wennberg, Basset-Seguin, Calzavara-Pinton, Gilaberte, Hofbauer, Hunger, Kar
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br Consequences of central apelin APJ modulation Regarding
2024-05-20
Consequences of central apelin/APJ modulation Regarding extra-hypothalamic actions, recent data demonstrate that the central apelin/APJ system could be a potential new target for the regulation of memory (Han et al., 2014). Then, intracerebroventricular (icv) apelin administration in mice impairs
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br Technical Note Fungal spoilage of dairy products
2024-05-20
Technical Note Fungal spoilage of dairy products remains a major concern for dairy manufacturers despite the use of preventive and control approaches, including the use of chemical preservatives. Among methods that are increasingly used by industries for microbial contaminant control, biopreserva
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Glycosylphosphatidylinositol GPI cell wall anchor synthesis
2024-05-20
Glycosylphosphatidylinositol (GPI) CAY10433 anchor synthesis pathway is another promising antifungal target. Novel inhibitors of Gwt1 and Mcd4, two enzymes in the GPI anchor pathway were identified by the chemical-genomics-based screening platform CaFT (Candida albicans fitness test) [89]. Screenin
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Several studies have explored the relationship between denta
2024-05-20
Several studies have explored the relationship between dental implants and MRONJ development. López-Cedrún JL et al. [13] reported that BRONJ developed after implant treatment in nine patients who were taking bisphosphonates orally. The mean interval between the initiation of treatment and the onset
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br Identification of the croaker mAR cDNA
2024-05-20
Identification of the croaker mAR cDNA Testosterone (T) was observed to alter steroidogenesis through a nongenomic mechanism (not blocked by the transcription inhibitor, actinomycin D) in Atlantic croaker ovarian tissues (Braun and Thomas, 2003). This action of T was mimicked by T conjugated to
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br Conclusion br Conflicts of interest br Introduction Alzhe
2024-05-18
Conclusion Conflicts of interest Introduction Alzheimer’s disease is the most common neurodegenerative condition known to cause dementia (Ferri et al., 2005). Alzheimer’s dementia typically presents with initial recent episodic memory deficits, word finding difficulty and later with apraxia
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br AhR Modulators It is now well recognized that
2024-05-18
AhR Modulators It is now well recognized that ligand-activated AhR induces an immune tolerance response by acting directly on the antigen-presenting DCs and indirectly by increasing the population of immunosuppressive Tregs 24, 95, 96. In addition to inhibiting the formation or depleting the AhR
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