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Vascular interventional radiology VIR laboratories perform a
2023-03-01
Vascular interventional radiology (VIR) laboratories perform a myriad of procedures ranging from simple tunneled peripherally inserted central catheter lines to complex transjugular intrahepatic portosystemic shunt placements. Infections are a common complication in the VIR environment; thus, the pr
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br Introduction Heart Failure HF is a
2023-03-01
Introduction Heart Failure (HF) is a major and growing health challenge in India and the developing countries. It is one of the most important causes of morbidity and mortality in the industrialized world. The incidence and prevalence estimates of HF are unreliable in India because of the lack of
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BGP-15 synthesis In addition to differential expression of A
2023-03-01
In addition to differential expression of AR protein primarily in surgical specimens, genetic alterations involving the AR gene have been documented in human BGP-15 synthesis cancer. Loss of heterozygosity at the AR locus was identified in all 3 informative cases of muscle-invasive bladder tumors, w
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Recent studies suggest that A caused
2023-03-01
Recent studies suggest that Aβ caused synapse damage as a consequence of aberrant cell signalling. As synthetic Aβ42 monomers activate the phosphatidylinositol-3-kinase pathway (Giuffrida et al., 2009) and insulin signalling (Giuffrida et al., 2012) it is possible that Aβ monomers and Aβ oligomers a
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AMP activated protein kinase AMPK is
2023-03-01
AMP-activated protein kinase (AMPK) is a key cellular energy sensor that maintains energy homeostasis at the cellular and whole-organism level (Hardie et al., 2012). Functionally, the AMPK pathway sustains adenosine triphosphate (ATP) production through activation of fatty herpes simplex virus oxid
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Previous studies have demonstrated that synaptic
2023-03-01
Previous studies have demonstrated that synaptic AMPARs can differ greatly in their mobility; some rapidly and constitutively Sulindac synthesis in and out of the synaptic membrane, while others remain somewhat stable in the synaptic membrane (Luscher et al., 1999, Luthi et al., 1999). We find that
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Consideration of the rate of product
2023-03-01
Consideration of the rate of product formation at different substrate concentrations and estimation of Michaelis-Menten parameters gives some insight into the possible mechanisms underlying the observed decreases in enzyme activity. Estimates based on two-substrate concentrations lack precision and
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However relatively little information is available concernin
2023-03-01
However, relatively little information is available concerning the biochemical properties and other features of such enzymes in Taeniid species. In the current report, a M17 leucine aminopeptidase gene of T. pisiformis (TpLAP) was cloned and expressed, and its enzymatic activity, biochemical propert
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In summary our data have shown
2023-03-01
In summary, our data have shown that one mechanism by which glucose may mediate monocyte–endothelial cell interaction in the retinal endothelial cells is via the 12/15-LO pathway Furthermore, our current and previously published data [20,22] indicate a differential role of endothelial 12/15-LO versu
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Imaging QTL studies may have several potential advantages
2023-03-01
Imaging QTL studies may have several potential advantages over case-control studies, including increased power . Imaging endophenotypes of disease in QTL studies can separate patients and normal subjects more accurately and therefore limit the confound of including asymptomatic subjects in the contr
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Liver plays a pivotal role
2023-03-01
Liver plays a pivotal role in metabolism of xenobiotic compounds, such as environmental contaminants and drugs. Some of these compounds generate hepatic damage and impair its function. It was well-known that 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) could induce pathological changes in mouse and ra
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Lee et al have demonstrated that APPL associates with AdipoR
2023-03-01
Lee et al. have demonstrated that APPL1 associates with AdipoR1 in Hek293 Nitecapone where both proteins have been overexpressed with suitable tags [16]. In contrast to recent data the formation of this complex is not enhanced by exogenous adiponectin [16], [33]. Knock-down of APPL1 reduces the lev
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Similarly Dilma et al tried to assess the diagnostic
2023-03-01
Similarly Dilmaç et al. [16] tried to assess the diagnostic value of adenosine deaminase activity in sputum of patients with pulmonary tuberculosis, their aim was to determine and compare sputum ADA activity in pulmonary tuberculosis, lung cancer and chronic obstructive pulmonary disease (COPD) pati
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Diabetes or inflammation is associated with up
2023-03-01
Diabetes or inflammation is associated with up-regulation of A2AAR (Pang et al., 2010). High levels of A2AARs are found in macrophages and microglial cells that are poised, on activation, to abrogate the immune response (Trincavelli et al., 2008). In addition, hyperglycemia is associated with increa
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Among different classes of pesticide organophosphates as wel
2023-03-01
Among different Phos-tag of pesticide, organophosphates as well as pyrethroids are more frequently used because of their high insecticidal property, low mammalian toxicity, less persistence and rapid biodegradability in the environment. These compounds are used extensively in agriculture supposed t
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