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While a role for YAP TAZ signaling in oligodendrocytes has
2021-12-14
While a role for YAP/TAZ signaling in oligodendrocytes has not been described, these apexbio calculator are also responsive to mechanical stimuli. OPC proliferation and migration can be altered by plating on substrates of varying stiffness [20], resulting in differentiation in a density-dependent m
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The GPR gene was included in our survey because
2021-12-14
The GPR35 gene was included in our survey because of its location immediately 3′ to CAPN10 and because it showed evidence of association with type 2 diabetes. Also, its expression in tissues including pancreatic islets and skeletal muscle is consistent with a possible role in type 2 diabetes. Our re
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Acknowledgments This research was supported by the
2021-12-14
Acknowledgments This research was supported by the Korea Research Institute of Chemical Technology (KRICT) funded by the Ministry of Science, ICT & Future Planning (KK1703-G00, KK1707-C05, SI1707-02, KK-1607-C09, and SKO1707C05) and a grant of the Korea Health Technology R&D Project through the Kor
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BIBR 1532 br Introduction In the treatment of patients with
2021-12-14
Introduction In the treatment of patients with AIDS and human immunodeficiency virus type 1 (HIV-1), anti-retroviral therapy (ART), which uses anti-HIV drugs such as protease inhibitors, integrase inhibitors and reverse transferase inhibitors, has made a major contribution. There are still some s
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br Methods br Results br Discussion LPD
2021-12-14
Methods Results Discussion LPD, in terms of insufficient secretion of progesterone by the CL, reflected by low serum progesterone levels can occur in IVF attempts using any kind of ovarian stimulation protocol (Fatemi et al., 2007, Garcia et al., 1981, Van der Linden et al., 2011). However,
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In vertebrates three cognate receptors or receptor like sequ
2021-12-14
In vertebrates, three cognate receptors or receptor-like sequences have been identified with distinct distributions and functions (Millar, 2005, Neill et al., 2001). Only two types of GnRHR occur in mammals, though (Morgan and Millar, 2004). The mammalian type I GnRHR shares over 80% amino interleuk
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Additionally increased GLO gene expression protein expressio
2021-12-14
Additionally, increased GLO1 gene expression, protein expression, and activity have been reported in a variety of cancers, including breast,22, 23, 24 pancreatic, melanoma, and prostate.27, 28, 29 Vince and Daluge proposed that inhibitors of GLO1 could serve as anti-tumor agents, by increasing conce
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C http www apexbt com media
2021-12-14
C136 is present in the joining region of two domains of NEIL1 and plays a critical role in the stability and dynamics of enzyme (Roy et al., 2007, Prakash et al., 2014). E181 resides in the conserved H2TH motif that binds to DNA and is very essential for enzyme activity. C136 is present in the near
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Always some extra effort may make great progress
2021-12-14
Always, some extra effort may make great progress in sensing platform, for example, Ma's group discovered luminescent iridium (Ⅲ) complexes which were highly selective for G-quadruplex DNA and Al3+, then they utilized these complexes to develop a series of G-quadruplex-based probes and chemosensor r
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We also demonstrated that inhibition of NAAG hydrolysis
2021-12-14
We also demonstrated that inhibition of NAAG hydrolysis to suppress glutamate production through a GCPII inhibitor is a viable target for cancer therapy. GCPII is also known as N-acetyl-L-aspartyl-L-glutamate peptidase I (NAALADase I) or NAAG peptidase (Pinto et al., 1996), and its increased express
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To evaluate SLC A abundance after transfection we performed
2021-12-14
To evaluate SLC45A1 abundance after transfection, we performed western blots. Transfected COS-7 casein kinase were lysed and separated for membrane fraction. Equal amounts of proteins from membrane fractions were resolved by SDS-PAGE, transferred to a nitrocellulose filter, and immunoblotted with a
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br Disclosure br Ghrelin System The existence of the ghrelin
2021-12-14
Disclosure Ghrelin System The existence of the ghrelin system has been demonstrated in many species through a variety of biochemical, anatomical, and genetic studies. It is a complex and intricate regulatory system comprised of several peptides, including mature ghrelin and its derivative des-
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64c mg br Introduction When human red blood cells hRBC are s
2021-12-14
Introduction When human red blood 64c mg (hRBC) are suspended in depolarising Ringers, they respond by opening a non-selective voltage-dependent cation pathway, the NSVDC channel, which is permeable to mono- and divalent cations [1], [2], [3]. In patch clamp experiments on excised hRBC inside-ou
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The release of FBPase and
2021-12-14
The release of FBPase and aldolase from subcellular structures of muscle was dependent on the presence of the crowding agent imitating the physiological conditions – PEG 8000 (Table 1). The amount of both enzymes associated with structures of muscle sodium butyrate was about 6–7 times higher in the
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br Introduction Lysine acetylation is an
2021-12-13
Introduction Lysine acetylation is an important post-translational modification that is found on numerous cellular proteins, including both histone and non-histone proteins [1], [2]. Dynamic acetylation and deacetylation is regulated by enzymes called histone acetyltransferases (HATs) as writers
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